Transcriptome and alternative splicing analysis of nucleus pulposus cells in response to high oxygen tension: Involvement of high oxygen tension in the pathogenesis of intervertebral disc degeneration

High oxygen tension caused by neovascularization in the microenvironment of intervertebral discs (IVDs) is associated with the pathogenesis of IVD degeneration (IDD). Pre-mRNAs undergo alternative splicing (AS) to produce structurally and functionally diverse mRNA and proteins. However, the precise...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Int J Mol Med
Prif Awduron: Feng, Chencheng, Zhang, Yang, Yang, Minghui, Lan, Minghong, Huang, Bo, Liu, Huan, Zhou, Yue
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: D.A. Spandidos 2018
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5881661/
https://ncbi.nlm.nih.gov/pubmed/29512703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2018.3523
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