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Transcriptome and alternative splicing analysis of nucleus pulposus cells in response to high oxygen tension: Involvement of high oxygen tension in the pathogenesis of intervertebral disc degeneration

High oxygen tension caused by neovascularization in the microenvironment of intervertebral discs (IVDs) is associated with the pathogenesis of IVD degeneration (IDD). Pre-mRNAs undergo alternative splicing (AS) to produce structurally and functionally diverse mRNA and proteins. However, the precise...

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Bibliografski detalji
Izdano u:Int J Mol Med
Glavni autori: Feng, Chencheng, Zhang, Yang, Yang, Minghui, Lan, Minghong, Huang, Bo, Liu, Huan, Zhou, Yue
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5881661/
https://ncbi.nlm.nih.gov/pubmed/29512703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2018.3523
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