Plasma cell output from germinal centers is regulated by signals from Tfh and stromal cells

Germinal centers (GCs) are the sites where B cells undergo affinity maturation. The regulation of cellular output from the GC is not well understood. Here, we show that from the earliest stages of the GC response, plasmablasts emerge at the GC–T zone interface (GTI). We define two main factors that...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Exp Med
Egile Nagusiak: Zhang, Yang, Tech, Laura, George, Laura A., Acs, Andreas, Durrett, Russell E., Hess, Henry, Walker, Lucy S.K., Tarlinton, David M., Fletcher, Anne L., Hauser, Anja Erika, Toellner, Kai-Michael
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Rockefeller University Press 2018
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5881458/
https://ncbi.nlm.nih.gov/pubmed/29549115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20160832
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