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SOCS3 deletion in B cells alters cytokine responses and germinal center output

B cell behaviour is fine-tuned by internal regulatory mechanisms and external cues such as cytokines and chemokines. SOCS3 is a key regulator of STAT3-dependent cytokine responses in many cell types, and has been reported to inhibit CXCL12-induced retention of immature B cells in the bone marrow. Us...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Jones, Sarah A., White, Christine A., Robb, Lorraine, Alexander, Warren S., Tarlinton, David M.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3254674/
https://ncbi.nlm.nih.gov/pubmed/22075701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102057
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