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SOCS3 deletion in B cells alters cytokine responses and germinal center output
B cell behaviour is fine-tuned by internal regulatory mechanisms and external cues such as cytokines and chemokines. SOCS3 is a key regulator of STAT3-dependent cytokine responses in many cell types, and has been reported to inhibit CXCL12-induced retention of immature B cells in the bone marrow. Us...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3254674/ https://ncbi.nlm.nih.gov/pubmed/22075701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102057 |
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