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Regulation of Multiple Cytokine Signalling Pathways by SOCS3 is Independent of SOCS2
Suppressor of cytokine signalling (SOCS) 3 is an essential regulator of cytokine signalling, and in turn its expression is tightly regulated. Data from overexpression studies in cell lines suggest that SOCS2 regulates SOCS3 protein degradation, by forming a molecular bridge to an E3 ubiquitin-ligase...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3412171/ https://ncbi.nlm.nih.gov/pubmed/19919527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/08977190903210954 |
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