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Regulation of Multiple Cytokine Signalling Pathways by SOCS3 is Independent of SOCS2

Suppressor of cytokine signalling (SOCS) 3 is an essential regulator of cytokine signalling, and in turn its expression is tightly regulated. Data from overexpression studies in cell lines suggest that SOCS2 regulates SOCS3 protein degradation, by forming a molecular bridge to an E3 ubiquitin-ligase...

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Bibliografske podrobnosti
Main Authors: KIU, HIU, GREENHALGH, CHRISTOPHER J., THAUS, ANNE, HILTON, DOUGLAS J., NICOLA, NICOS A., ALEXANDER, WARREN S., ROBERTS, ANDREW W.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412171/
https://ncbi.nlm.nih.gov/pubmed/19919527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/08977190903210954
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