Plasma cell output from germinal centers is regulated by signals from Tfh and stromal cells

Germinal centers (GCs) are the sites where B cells undergo affinity maturation. The regulation of cellular output from the GC is not well understood. Here, we show that from the earliest stages of the GC response, plasmablasts emerge at the GC–T zone interface (GTI). We define two main factors that...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Zhang, Yang, Tech, Laura, George, Laura A., Acs, Andreas, Durrett, Russell E., Hess, Henry, Walker, Lucy S.K., Tarlinton, David M., Fletcher, Anne L., Hauser, Anja Erika, Toellner, Kai-Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5881458/
https://ncbi.nlm.nih.gov/pubmed/29549115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20160832
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