Plasma cell output from germinal centers is regulated by signals from Tfh and stromal cells

Germinal centers (GCs) are the sites where B cells undergo affinity maturation. The regulation of cellular output from the GC is not well understood. Here, we show that from the earliest stages of the GC response, plasmablasts emerge at the GC–T zone interface (GTI). We define two main factors that...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Exp Med
Prif Awduron: Zhang, Yang, Tech, Laura, George, Laura A., Acs, Andreas, Durrett, Russell E., Hess, Henry, Walker, Lucy S.K., Tarlinton, David M., Fletcher, Anne L., Hauser, Anja Erika, Toellner, Kai-Michael
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Rockefeller University Press 2018
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5881458/
https://ncbi.nlm.nih.gov/pubmed/29549115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20160832
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