Metabolic consequences of HIF silencing in a triple negative human breast cancer xenograft

Hypoxia is frequently encountered in tumors and results in the stabilization of hypoxia inducible factors (HIFs). These factors transcriptionally activate genes that allow cells to adapt to hypoxia. In cancers, hypoxia and HIFs have been associated with increased invasion, metastasis, and resistance...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Bharti, Santosh K., Mironchik, Yelena, Wildes, Flonne, Penet, Marie-France, Goggins, Eibhlin, Krishnamachary, Balaji, Bhujwalla, Zaver M.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2018
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880607/
https://ncbi.nlm.nih.gov/pubmed/29632647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24569
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