Metabolic consequences of HIF silencing in a triple negative human breast cancer xenograft

Hypoxia is frequently encountered in tumors and results in the stabilization of hypoxia inducible factors (HIFs). These factors transcriptionally activate genes that allow cells to adapt to hypoxia. In cancers, hypoxia and HIFs have been associated with increased invasion, metastasis, and resistance...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Bharti, Santosh K., Mironchik, Yelena, Wildes, Flonne, Penet, Marie-France, Goggins, Eibhlin, Krishnamachary, Balaji, Bhujwalla, Zaver M.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880607/
https://ncbi.nlm.nih.gov/pubmed/29632647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24569
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