Metabolic consequences of HIF silencing in a triple negative human breast cancer xenograft

Hypoxia is frequently encountered in tumors and results in the stabilization of hypoxia inducible factors (HIFs). These factors transcriptionally activate genes that allow cells to adapt to hypoxia. In cancers, hypoxia and HIFs have been associated with increased invasion, metastasis, and resistance...

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發表在:Oncotarget
Main Authors: Bharti, Santosh K., Mironchik, Yelena, Wildes, Flonne, Penet, Marie-France, Goggins, Eibhlin, Krishnamachary, Balaji, Bhujwalla, Zaver M.
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2018
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Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880607/
https://ncbi.nlm.nih.gov/pubmed/29632647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24569
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