Metabolic consequences of HIF silencing in a triple negative human breast cancer xenograft

Hypoxia is frequently encountered in tumors and results in the stabilization of hypoxia inducible factors (HIFs). These factors transcriptionally activate genes that allow cells to adapt to hypoxia. In cancers, hypoxia and HIFs have been associated with increased invasion, metastasis, and resistance...

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Udgivet i:Oncotarget
Main Authors: Bharti, Santosh K., Mironchik, Yelena, Wildes, Flonne, Penet, Marie-France, Goggins, Eibhlin, Krishnamachary, Balaji, Bhujwalla, Zaver M.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2018
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Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880607/
https://ncbi.nlm.nih.gov/pubmed/29632647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24569
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