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Noninflammatory Changes of Microglia Are Sufficient to Cause Epilepsy
Microglia are well known to play a critical role in maintaining brain homeostasis. However, their role in epileptogenesis has yet to be determined. Here, we demonstrate that elevated mTOR signaling in mouse microglia leads to phenotypic changes, including an amoeboid-like morphology, increased proli...
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| Publicado en: | Cell Rep |
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| Autores principales: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5880308/ https://ncbi.nlm.nih.gov/pubmed/29466735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.02.004 |
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