Microglial mTOR is Neuronal Protective and Antiepileptogenic in the Pilocarpine Model of Temporal Lobe Epilepsy

Excessive activation of mammalian target of rapamycin (mTOR) signaling is epileptogenic in genetic epilepsy. However, the exact role of microglial mTOR in acquired epilepsy remains to be clarified. In the present study, we found that mTOR is strongly activated in microglia following excitatory injur...

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Publicat a:J Neurosci
Autors principals: Zhao, Xiao-Feng, Liao, Yuan, Alam, Mahabub Maraj, Mathur, Ramkumar, Feustel, Paul, Mazurkiewicz, Joseph E., Adamo, Matthew A., Zhu, Xinjun C., Huang, Yunfei
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2020
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7531547/
https://ncbi.nlm.nih.gov/pubmed/32868461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2754-19.2020
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