Microglial mTOR is Neuronal Protective and Antiepileptogenic in the Pilocarpine Model of Temporal Lobe Epilepsy

Excessive activation of mammalian target of rapamycin (mTOR) signaling is epileptogenic in genetic epilepsy. However, the exact role of microglial mTOR in acquired epilepsy remains to be clarified. In the present study, we found that mTOR is strongly activated in microglia following excitatory injur...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Zhao, Xiao-Feng, Liao, Yuan, Alam, Mahabub Maraj, Mathur, Ramkumar, Feustel, Paul, Mazurkiewicz, Joseph E., Adamo, Matthew A., Zhu, Xinjun C., Huang, Yunfei
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7531547/
https://ncbi.nlm.nih.gov/pubmed/32868461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2754-19.2020
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