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Finding a better drug for epilepsy: The mTOR pathway as an antiepileptogenic target

The mTOR signaling pathway regulates cell growth, differentiation, proliferation and metabolism. Loss of function mutations in upstream regulators of mTOR have been highly associated with dysplasias, epilepsy and neurodevelopmental disorders. These include tuberous sclerosis, which is due to mutatio...

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Detalhes bibliográficos
Main Authors: Galanopoulou, Aristea S., Gorter, Jan A., Cepeda, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3389589/
https://ncbi.nlm.nih.gov/pubmed/22578218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1528-1167.2012.03506.x
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