Combinatorial Omics Analysis Reveals Perturbed Lysosomal Homeostasis in Collagen VII-deficient Keratinocytes

The extracellular matrix protein collagen VII is part of the microenvironment of stratified epithelia and critical in organismal homeostasis. Mutations in the encoding gene COL7A1 lead to the skin disorder dystrophic epidermolysis bullosa (DEB), are linked to skin fragility and progressive inflammat...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Thriene, Kerstin, Grüning, Björn Andreas, Bornert, Olivier, Erxleben, Anika, Leppert, Juna, Athanasiou, Ioannis, Weber, Ekkehard, Kiritsi, Dimitra, Nyström, Alexander, Reinheckel, Thomas, Backofen, Rolf, Has, Cristina, Bruckner-Tuderman, Leena, Dengjel, Jörn
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880109/
https://ncbi.nlm.nih.gov/pubmed/29326176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA117.000437
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