Losartan ameliorates dystrophic epidermolysis bullosa and uncovers new disease mechanisms

Genetic loss of collagen VII causes recessive dystrophic epidermolysis bullosa (RDEB)—a severe skin fragility disorder associated with lifelong blistering and disabling progressive soft tissue fibrosis. Causative therapies for this complex disorder face major hurdles, and clinical implementation rem...

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Dettagli Bibliografici
Pubblicato in:EMBO Mol Med
Autori principali: Nyström, Alexander, Thriene, Kerstin, Mittapalli, Venugopal, Kern, Johannes S, Kiritsi, Dimitra, Dengjel, Jörn, Bruckner-Tuderman, Leena
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons, Ltd 2015
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568953/
https://ncbi.nlm.nih.gov/pubmed/26194911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201505061
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