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Losartan ameliorates dystrophic epidermolysis bullosa and uncovers new disease mechanisms

Genetic loss of collagen VII causes recessive dystrophic epidermolysis bullosa (RDEB)—a severe skin fragility disorder associated with lifelong blistering and disabling progressive soft tissue fibrosis. Causative therapies for this complex disorder face major hurdles, and clinical implementation rem...

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Publicat a:EMBO Mol Med
Autors principals: Nyström, Alexander, Thriene, Kerstin, Mittapalli, Venugopal, Kern, Johannes S, Kiritsi, Dimitra, Dengjel, Jörn, Bruckner-Tuderman, Leena
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons, Ltd 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568953/
https://ncbi.nlm.nih.gov/pubmed/26194911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201505061
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