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Combinatorial Omics Analysis Reveals Perturbed Lysosomal Homeostasis in Collagen VII-deficient Keratinocytes

The extracellular matrix protein collagen VII is part of the microenvironment of stratified epithelia and critical in organismal homeostasis. Mutations in the encoding gene COL7A1 lead to the skin disorder dystrophic epidermolysis bullosa (DEB), are linked to skin fragility and progressive inflammat...

詳細記述

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書誌詳細
出版年:Mol Cell Proteomics
主要な著者: Thriene, Kerstin, Grüning, Björn Andreas, Bornert, Olivier, Erxleben, Anika, Leppert, Juna, Athanasiou, Ioannis, Weber, Ekkehard, Kiritsi, Dimitra, Nyström, Alexander, Reinheckel, Thomas, Backofen, Rolf, Has, Cristina, Bruckner-Tuderman, Leena, Dengjel, Jörn
フォーマット: Artigo
言語:Inglês
出版事項: The American Society for Biochemistry and Molecular Biology 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880109/
https://ncbi.nlm.nih.gov/pubmed/29326176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA117.000437
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