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Axogenic mechanism enhances retinal ganglion cell excitability during early progression in glaucoma

Diseases of the brain involve early axon dysfunction that often precedes outright degeneration. Pruning of dendrites and their synapses represents a potential driver of axonopathy by reducing activity. Optic nerve degeneration in glaucoma, the world’s leading cause of irreversible blindness, involve...

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Podrobná bibliografie
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Risner, Michael L., Pasini, Silvia, Cooper, Melissa L., Lambert, Wendi S., Calkins, David J.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877940/
https://ncbi.nlm.nih.gov/pubmed/29463759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1714888115
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