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Axogenic mechanism enhances retinal ganglion cell excitability during early progression in glaucoma

Diseases of the brain involve early axon dysfunction that often precedes outright degeneration. Pruning of dendrites and their synapses represents a potential driver of axonopathy by reducing activity. Optic nerve degeneration in glaucoma, the world’s leading cause of irreversible blindness, involve...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Risner, Michael L., Pasini, Silvia, Cooper, Melissa L., Lambert, Wendi S., Calkins, David J.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877940/
https://ncbi.nlm.nih.gov/pubmed/29463759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1714888115
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