Neuroprotection by Wld(S) depends on retinal ganglion cell type and age in glaucoma

BACKGROUND: Early challenges to axonal physiology, active transport, and ultrastructure are endemic to age-related neurodegenerative disorders, including those affecting the optic nerve. Chief among these, glaucoma causes irreversible vision loss through sensitivity to intraocular pressure (IOP) tha...

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Foilsithe in:Mol Neurodegener
Main Authors: Risner, Michael L., Pasini, Silvia, McGrady, Nolan R., D’Alessandro, Karis B., Yao, Vincent, Cooper, Melissa L., Calkins, David J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2021
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8180099/
https://ncbi.nlm.nih.gov/pubmed/34090501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-021-00459-y
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