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Axogenic mechanism enhances retinal ganglion cell excitability during early progression in glaucoma

Diseases of the brain involve early axon dysfunction that often precedes outright degeneration. Pruning of dendrites and their synapses represents a potential driver of axonopathy by reducing activity. Optic nerve degeneration in glaucoma, the world’s leading cause of irreversible blindness, involve...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Risner, Michael L., Pasini, Silvia, Cooper, Melissa L., Lambert, Wendi S., Calkins, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877940/
https://ncbi.nlm.nih.gov/pubmed/29463759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1714888115
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