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Elevated ocular pressure reduces voltage-gated sodium channel NaV1.2 protein expression in retinal ganglion cell axons

Glaucoma is an age-related neurodegenerative disease that is commonly associated with sensitivity to intraocular pressure. The disease selectively targets retinal ganglion cells (RGCs) and constituent axons. RGC axons are rich in voltage-gated sodium channels, which are essential for action potentia...

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書目詳細資料
發表在:Exp Eye Res
Main Authors: Risner, Michael L., McGrady, Nolan R., Pasini, Silvia, Lambert, Wendi S., Calkins, David J.
格式: Artigo
語言:Inglês
出版: 2019
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6957720/
https://ncbi.nlm.nih.gov/pubmed/31734278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2019.107873
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