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Gold nanoparticles stabilize peptide-drug-conjugates for sustained targeted drug delivery to cancer cells

BACKGROUND: Peptide-drug-conjugates (PDCs) are being developed as an effective strategy to specifically deliver cytotoxic drugs to cancer cells. However one of the challenges to their successful application is the relatively low stability of peptides in the blood, liver and kidneys. Since AuNPs seem...

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Podrobná bibliografie
Vydáno v:J Nanobiotechnology
Hlavní autoři: Kalimuthu, Kalishwaralal, Lubin, Bat-Chen, Bazylevich, Andrii, Gellerman, Gary, Shpilberg, Ofer, Luboshits, Galia, Firer, Michael A.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877385/
https://ncbi.nlm.nih.gov/pubmed/29602308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-018-0362-1
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