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Gold nanoparticles stabilize peptide-drug-conjugates for sustained targeted drug delivery to cancer cells

BACKGROUND: Peptide-drug-conjugates (PDCs) are being developed as an effective strategy to specifically deliver cytotoxic drugs to cancer cells. However one of the challenges to their successful application is the relatively low stability of peptides in the blood, liver and kidneys. Since AuNPs seem...

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Detalles Bibliográficos
Publicado en:J Nanobiotechnology
Main Authors: Kalimuthu, Kalishwaralal, Lubin, Bat-Chen, Bazylevich, Andrii, Gellerman, Gary, Shpilberg, Ofer, Luboshits, Galia, Firer, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877385/
https://ncbi.nlm.nih.gov/pubmed/29602308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-018-0362-1
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