Gold nanoparticles stabilize peptide-drug-conjugates for sustained targeted drug delivery to cancer cells

BACKGROUND: Peptide-drug-conjugates (PDCs) are being developed as an effective strategy to specifically deliver cytotoxic drugs to cancer cells. However one of the challenges to their successful application is the relatively low stability of peptides in the blood, liver and kidneys. Since AuNPs seem...

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Détails bibliographiques
Publié dans:J Nanobiotechnology
Auteurs principaux: Kalimuthu, Kalishwaralal, Lubin, Bat-Chen, Bazylevich, Andrii, Gellerman, Gary, Shpilberg, Ofer, Luboshits, Galia, Firer, Michael A.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2018
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877385/
https://ncbi.nlm.nih.gov/pubmed/29602308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-018-0362-1
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