Gold nanoparticles stabilize peptide-drug-conjugates for sustained targeted drug delivery to cancer cells

BACKGROUND: Peptide-drug-conjugates (PDCs) are being developed as an effective strategy to specifically deliver cytotoxic drugs to cancer cells. However one of the challenges to their successful application is the relatively low stability of peptides in the blood, liver and kidneys. Since AuNPs seem...

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Dades bibliogràfiques
Publicat a:J Nanobiotechnology
Autors principals: Kalimuthu, Kalishwaralal, Lubin, Bat-Chen, Bazylevich, Andrii, Gellerman, Gary, Shpilberg, Ofer, Luboshits, Galia, Firer, Michael A.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877385/
https://ncbi.nlm.nih.gov/pubmed/29602308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-018-0362-1
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