Toward the development of a novel non-RGD cyclic peptide drug conjugate for treatment of human metastatic melanoma

The newly discovered short (9 amino acid) non-RGD S-S bridged cyclic peptide ALOS-4 (H-cycl(Cys-Ser-Ser-Ala-Gly-Ser-Leu-Phe-Cys)-OH), which binds to integrin α(v)β(3) is investigated as peptide carrier for targeted drug delivery against human metastatic melanoma. ALOS4 binds specifically the α(v)β(3...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Redko, Boris, Tuchinsky, Helena, Segal, Tamar, Tobi, Dror, Luboshits, Galia, Ashur-Fabian, Osnat, Pinhasov, Albert, Gerlitz, Gabi, Gellerman, Gary
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352194/
https://ncbi.nlm.nih.gov/pubmed/27768593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12748
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