SIRT6 facilitates directional telomere movement upon oxidative damage

Oxidative damage to telomeres leads to telomere attrition and genomic instability, resulting in poor cell viability. Telomere dynamics contribute to the maintenance of telomere integrity; however, whether oxidative damage induces telomere movement and how telomere mobility is regulated remain poorly...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Gao, Ying, Tan, Jun, Jin, Jingyi, Ma, Hongqiang, Chen, Xiukai, Leger, Brittany, Xu, Jianquan, Spagnol, Stephen T., Dahl, Kris Noel, Levine, Arthur S., Liu, Yang, Lan, Li
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5876328/
https://ncbi.nlm.nih.gov/pubmed/29599436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23602-0
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