SSRP1 cooperates with PARP and XRCC1 to facilitate single strand DNA break repair by chromatin priming

DNA single strand breaks (SSB) are the most common form of DNA damage, requiring repair processes that to initiate must overcome chromatin barriers. The FACT complex comprised of the SSRP1 and SPT16 proteins are important for maintaining chromatin integrity, with SSRP1 acting as an histone H2A/H2B c...

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Publicado en:Cancer Res
Main Authors: Gao, Ying, Li, Changling, Wei, Leizhen, Teng, Yaqun, Nakajima, Satoshi, Chen, Xiukai, Xu, Jianquan, Legar, Brittany, Ma, Hongqiang, Spagnol, Stephen T., Wan, Yong, Dahl, Kris Noel, Liu, Yang, Levine, Arthur S., Lan, Li
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500382/
https://ncbi.nlm.nih.gov/pubmed/28416484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-3128
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