Načítá se...
Antisense suppression of glial fibrillary acidic protein as a treatment for Alexander disease
OBJECTIVE: Alexander disease is a fatal leukodystrophy caused by autosomal dominant gain-of-function mutations in the gene for glial fibrillary acidic protein (GFAP), an intermediate filament protein primarily expressed in astrocytes of the central nervous system. A key feature of pathogenesis is ov...
Uloženo v:
| Vydáno v: | Ann Neurol |
|---|---|
| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2018
|
| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5876100/ https://ncbi.nlm.nih.gov/pubmed/29226998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.25118 |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!
|