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The MFHR1 Fusion Protein Is a Novel Synthetic Multitarget Complement Inhibitor with Therapeutic Potential

The complement system is essential for host defense, but uncontrolled complement system activation leads to severe, mostly renal pathologies, such as atypical hemolytic uremic syndrome or C3 glomerulopathy. Here, we investigated a novel combinational approach to modulate complement activation by tar...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Am Soc Nephrol
मुख्य लेखकों: Michelfelder, Stefan, Fischer, Friedericke, Wäldin, Astrid, Hörle, Kim V., Pohl, Martin, Parsons, Juliana, Reski, Ralf, Decker, Eva L., Zipfel, Peter F., Skerka, Christine, Häffner, Karsten
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society of Nephrology 2018
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5875950/
https://ncbi.nlm.nih.gov/pubmed/29335241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2017070738
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