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Recombinant Production of MFHR1, A Novel Synthetic Multitarget Complement Inhibitor, in Moss Bioreactors

The human complement system is an important part of the immune system responsible for lysis and elimination of invading microorganisms and apoptotic body cells. Improper activation of the system due to deficiency, mutations, or autoantibodies of complement regulators, mainly factor H (FH) and FH-rel...

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Dades bibliogràfiques
Publicat a:Front Plant Sci
Autors principals: Top, Oguz, Parsons, Juliana, Bohlender, Lennard L., Michelfelder, Stefan, Kopp, Phillipp, Busch-Steenberg, Christian, Hoernstein, Sebastian N. W., Zipfel, Peter F., Häffner, Karsten, Reski, Ralf, Decker, Eva L.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6436476/
https://ncbi.nlm.nih.gov/pubmed/30949184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpls.2019.00260
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