Recombinant Production of MFHR1, A Novel Synthetic Multitarget Complement Inhibitor, in Moss Bioreactors

The human complement system is an important part of the immune system responsible for lysis and elimination of invading microorganisms and apoptotic body cells. Improper activation of the system due to deficiency, mutations, or autoantibodies of complement regulators, mainly factor H (FH) and FH-rel...

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Détails bibliographiques
Publié dans:Front Plant Sci
Auteurs principaux: Top, Oguz, Parsons, Juliana, Bohlender, Lennard L., Michelfelder, Stefan, Kopp, Phillipp, Busch-Steenberg, Christian, Hoernstein, Sebastian N. W., Zipfel, Peter F., Häffner, Karsten, Reski, Ralf, Decker, Eva L.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2019
Sujets:
Plant Science
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6436476/
https://ncbi.nlm.nih.gov/pubmed/30949184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpls.2019.00260
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