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Novel PAMAM-PEG-Peptide Conjugates for siRNA Delivery Targeted to the Transferrin and Epidermal Growth Factor Receptors

The transferrin (TfR) and epidermal growth factor receptors (EGFR) are known to be overexpressed on the surface of a wide variety of tumor cells. Therefore, the peptides B6 (TfR specific) and GE11 (targeted to the EGFR) were linked to the PAMAM (polyamidoamine) structure via a polyethylenglycol (PEG...

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Detalhes bibliográficos
Publicado no:J Pers Med
Main Authors: Urbiola, Koldo, Blanco-Fernández, Laura, Ogris, Manfred, Rödl, Wolfgang, Wagner, Ernst, Tros de Ilarduya, Conchita
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5872078/
https://ncbi.nlm.nih.gov/pubmed/29315261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jpm8010004
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