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Multifunctional Triblock Nanocarrier (PAMAM-PEG-PLL) for the Efficient Intracellular siRNA Delivery and Gene Silencing

[Image: see text] A novel triblock poly(amido amine)-poly(ethylene glycol)-poly-l-lysine (PAMAM-PEG-PLL) nanocarrier was designed, synthesized, and evaluated for the delivery of siRNA. The design of the nanocarrier is unique and provides a solution to most of the common problems associated with the...

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Bibliographic Details
Main Authors: Patil, Mahesh L., Zhang, Min, Minko, Tamara
Format: Artigo
Language:Inglês
Published: American Chemical Society 2011
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062392/
https://ncbi.nlm.nih.gov/pubmed/21322531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn102711d
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