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Internally Cationic Polyamidoamine PAMAM-OH Dendrimers for siRNA Delivery: Effect of the Degree of Quaternization and Cancer Targeting
A novel cancer targeted, internally cationic, and surface neutral Polyamidoamine (PAMAM) dendrimer was designed, synthesized, and evaluated as a nanocarrier for the targeted intracellular delivery of siRNA. The dendrimer contained a synthetic analog of Luteinizing Hormone-Releasing Hormone as cancer...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2653103/ https://ncbi.nlm.nih.gov/pubmed/19159248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm8009973 |
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