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Tuning DNA Condensation with Zwitterionic Polyamidoamine (zPAMAM) Dendrimers

Cationic dendrimers are promising vectors for non-viral gene due to their well-defined size and chemistry. We have synthesized a series of succinylated fourth generation (G4) PAMAM dendrimers to control the DNA packaging in dendriplexes, allowing us to probe the role of charge on DNA packaging. The...

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Bibliografische gegevens
Gepubliceerd in:Macromolecules
Hoofdauteurs: An, Min, Tonga, Gulen Yesilbag, Parkin, Sean R., Rotello, Vincent M., DeRouchey, Jason E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6349388/
https://ncbi.nlm.nih.gov/pubmed/30700915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.macromol.7b01470
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