Surface-Engineered Targeted PPI Dendrimer for Efficient Intracellular and Intratumoral siRNA Delivery

Low penetration ability of Small Interfering RNA (siRNA) through the cellular plasma membrane combined with its limited stability in blood, limits the effectiveness of the systemic delivery of siRNA. In order to overcome such difficulties, we constructed a nanocarrier-based delivery system by taking...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Taratula, Oleh, Garbuzenko, Olga B., Kirkpatrick, Paul, Pandya, Ipsit, Savla, Ronak, Pozharov, Vitaly P., He, Huixin, Minko, Tamara
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787988/
https://ncbi.nlm.nih.gov/pubmed/19567257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2009.06.019
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge