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Lipid Modified Triblock PAMAM-Based Nanocarriers for siRNA Drug Co-Delivery

RNA interference by short interfering RNA (siRNA) holds promise to attenuate production of specific target proteins but is challenging in practice owing to the barriers for its efficient intracellular delivery. We have synthesized a tri-block co-polymeric system, poly(amidoamine) dendrimer (generati...

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Bibliografiske detaljer
Main Authors: Biswas, Swati, Deshpande, Pranali P., Navarro, Gemma, Dodwadkar, Namita S., Torchilin, Vladimir P.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511617/
https://ncbi.nlm.nih.gov/pubmed/23137395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2012.10.024
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