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Interaction of microtubule depolymerizing agent indanocine with different human αβ tubulin isotypes

Tubulin isotypes are known to regulate the stability and dynamics of microtubules, and are also involved in the development of resistance against microtubule-targeted cancer drugs. Indanocine, a potent microtubule depolymerizing agent, is highly active against multidrug-resistant (MDR) cancer cells...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Kumbhar, Bajarang Vasant, Panda, Dulal, Kunwar, Ambarish
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870988/
https://ncbi.nlm.nih.gov/pubmed/29584771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0194934
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