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Interaction of microtubule depolymerizing agent indanocine with different human αβ tubulin isotypes

Tubulin isotypes are known to regulate the stability and dynamics of microtubules, and are also involved in the development of resistance against microtubule-targeted cancer drugs. Indanocine, a potent microtubule depolymerizing agent, is highly active against multidrug-resistant (MDR) cancer cells...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Kumbhar, Bajarang Vasant, Panda, Dulal, Kunwar, Ambarish
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870988/
https://ncbi.nlm.nih.gov/pubmed/29584771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0194934
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