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Interaction of microtubule depolymerizing agent indanocine with different human αβ tubulin isotypes

Tubulin isotypes are known to regulate the stability and dynamics of microtubules, and are also involved in the development of resistance against microtubule-targeted cancer drugs. Indanocine, a potent microtubule depolymerizing agent, is highly active against multidrug-resistant (MDR) cancer cells...

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發表在:PLoS One
Main Authors: Kumbhar, Bajarang Vasant, Panda, Dulal, Kunwar, Ambarish
格式: Artigo
語言:Inglês
出版: Public Library of Science 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870988/
https://ncbi.nlm.nih.gov/pubmed/29584771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0194934
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