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Interaction of microtubule depolymerizing agent indanocine with different human αβ tubulin isotypes
Tubulin isotypes are known to regulate the stability and dynamics of microtubules, and are also involved in the development of resistance against microtubule-targeted cancer drugs. Indanocine, a potent microtubule depolymerizing agent, is highly active against multidrug-resistant (MDR) cancer cells...
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| Publicado en: | PLoS One |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5870988/ https://ncbi.nlm.nih.gov/pubmed/29584771 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0194934 |
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