Baicalin reverses the impairment of synaptogenesis induced by dopamine burden via the stimulation of GABA(A)R–TrkB interaction in minimal hepatic encephalopathy

BACKGROUND: It has been reported that D1 receptor (D(1)R) activation reduces GABA(A) receptor (GABA(A)R) current, and baicalin (BAI) displays therapeutic efficacy in diseases involving cognitive impairment. METHODS: We investigated the mechanisms by which BAI could improve DA-induced minimal hepatic...

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Bibliografiske detaljer
Udgivet i:Psychopharmacology (Berl)
Main Authors: Ding, Saidan, Zhuge, Weishan, Hu, Jiangnan, Yang, Jianjing, Wang, Xuebao, Wen, Fangfang, Wang, Chengde, Zhuge, Qichuan
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2018
Fag:
Original Investigation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5869945/
https://ncbi.nlm.nih.gov/pubmed/29404643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-018-4833-8
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