DA Negatively Regulates IGF-I Actions Implicated in Cognitive Function via Interaction of PSD95 and nNOS in Minimal Hepatic Encephalopathy

Insulin-like growth factor I (IGF-I) has been positively correlated with cognitive ability. Cognitive decline in minimal hepatic encephalopathy (MHE) was shown to be induced by elevated intracranial dopamine (DA). The beneficial effect of IGF-I signaling in MHE remains unknown. In this study, we fou...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Ding, Saidan, Zhuge, Weishan, Wang, Xuebao, Yang, Jianjing, Lin, Yuanshao, Wang, Chengde, Hu, Jiangnan, Zhuge, Qichuan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5592740/
https://ncbi.nlm.nih.gov/pubmed/28932186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2017.00258
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