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Baicalin reverses the impairment of synaptogenesis induced by dopamine burden via the stimulation of GABA(A)R–TrkB interaction in minimal hepatic encephalopathy
BACKGROUND: It has been reported that D1 receptor (D(1)R) activation reduces GABA(A) receptor (GABA(A)R) current, and baicalin (BAI) displays therapeutic efficacy in diseases involving cognitive impairment. METHODS: We investigated the mechanisms by which BAI could improve DA-induced minimal hepatic...
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| Publicado no: | Psychopharmacology (Berl) |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5869945/ https://ncbi.nlm.nih.gov/pubmed/29404643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-018-4833-8 |
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