Oligomer-prone E57K-mutant alpha-synuclein exacerbates integration deficit of adult hippocampal newborn neurons in transgenic mice

In the adult mammalian hippocampus, new neurons are constantly added to the dentate gyrus. Adult neurogenesis is impaired in several neurodegenerative mouse models including α-synuclein (a-syn) transgenic mice. Among different a-syn species, a-syn oligomers were reported to be the most toxic species...

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Detaylı Bibliyografya
Yayımlandı:Brain Struct Funct
Asıl Yazarlar: Regensburger, Martin, Schreglmann, Sebastian R., Stoll, Svenja, Rockenstein, Edward, Loskarn, Sandra, Xiang, Wei, Masliah, Eliezer, Winner, Beate
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer Berlin Heidelberg 2017
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5869938/
https://ncbi.nlm.nih.gov/pubmed/29124353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00429-017-1561-5
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