Comparative pharmacokinetics and safety assessment of transdermal berberine and dihydroberberine

The natural alkaloid berberine has been ascribed numerous health benefits including lipid and cholesterol reduction and improved insulin sensitivity in diabetics. However, oral (PO) administration of berberine is hindered by poor bioavailability and increasing dose often elicits gastro-intestinal si...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Buchanan, Beth, Meng, Qingfang, Poulin, Mathieu-Marc, Zuccolo, Jonathan, Azike, Chike Godwin, Gabriele, Joseph, Baranowski, David Charles
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2018
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5868852/
https://ncbi.nlm.nih.gov/pubmed/29579096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0194979
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