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Comparative pharmacokinetics and safety assessment of transdermal berberine and dihydroberberine
The natural alkaloid berberine has been ascribed numerous health benefits including lipid and cholesterol reduction and improved insulin sensitivity in diabetics. However, oral (PO) administration of berberine is hindered by poor bioavailability and increasing dose often elicits gastro-intestinal si...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5868852/ https://ncbi.nlm.nih.gov/pubmed/29579096 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0194979 |
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