Oncolytic reovirus as a combined antiviral and anti-tumour agent for the treatment of liver cancer

OBJECTIVE: Oncolytic viruses (OVs) represent promising, proinflammatory cancer treatments. Here, we explored whether OV-induced innate immune responses could simultaneously inhibit HCV while suppressing hepatocellular carcinoma (HCC). Furthermore, we extended this exemplar to other models of virus-a...

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Veröffentlicht in:Gut
Hauptverfasser: Samson, Adel, Bentham, Matthew J, Scott, Karen, Nuovo, Gerard, Bloy, Abigail, Appleton, Elizabeth, Adair, Robert A, Dave, Rajiv, Peckham-Cooper, Adam, Toogood, Giles, Nagamori, Seishi, Coffey, Matthew, Vile, Richard, Harrington, Kevin, Selby, Peter, Errington-Mais, Fiona, Melcher, Alan, Griffin, Stephen
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Publishing Group 2018
Schlagworte:
Hepatology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5868283/
https://ncbi.nlm.nih.gov/pubmed/27902444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2016-312009
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