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Cytotoxic and immune-mediated killing of human colorectal cancer by reovirus-loaded blood and liver mononuclear cells

Reovirus is a promising oncolytic virus, acting by both direct and immune-mediated mechanisms, although its potential may be limited by inactivation after systemic delivery. Our study addressed whether systemically delivered reovirus might be shielded from neutralising antibodies by cell carriage an...

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Detalhes bibliográficos
Main Authors: Adair, Robert A., Scott, Karen J., Fraser, Sheila, Errington-Mais, Fiona, Pandha, Hardev, Coffey, Matt, Selby, Peter, Cook, Graham P., Vile, Richard, Harrington, Kevin J., Toogood, Giles, Melcher, Alan A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3891508/
https://ncbi.nlm.nih.gov/pubmed/23114986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.27918
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