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Reovirus-Mediated Cytotoxicity and Enhancement of Innate Immune Responses Against Acute Myeloid Leukemia

Reovirus is a naturally occurring oncolytic virus that has shown preclinical efficacy in the treatment of a wide range of tumor types and has now reached phase III testing in clinical trials. The anti-cancer activity of reovirus has been attributed to both its direct oncolytic activity and the enhan...

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Detalhes bibliográficos
Main Authors: Hall, Kathryn, Scott, Karen J., Rose, Ailsa, Desborough, Michael, Harrington, Kevin, Pandha, Hardev, Parrish, Christopher, Vile, Richard, Coffey, Matt, Bowen, David, Errington-Mais, Fiona, Melcher, Alan A.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3559227/
https://ncbi.nlm.nih.gov/pubmed/23515241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/biores.2012.0205
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